Two types of mixed gonad dysgenesis (true hermaphroditism) of the dog - a clinical case
نویسنده
چکیده
Mixed gonad dysgenesis or true hermaphroditism is the heaviest sexual chromosome syndrome in which one individual animal has simultaneously two fully functional types of reproductive tissue, which is presented with strong disorders in a dog’s sexual development. With the expansion of castration of homeless and domestic dogs, as well as with the advancement in diagnostic imaging methods various genital abnormalities and dysgeneses in dogs of different breed affiliation can be detected. Hormonal imbalance, abnormal and delayed development, and ambiguous genital organs of a dog can be established. Sometimes they appear with nonspecific symptoms which are hard to differentiate from other disorders of the urinary and reproductive organs. The two types of true hermaphroditism as first manifest with male phenotype, second was develop with female phenotype were detected. The different types of sexually chromosome syndrome in the dog should be known and researched in dog`s veterinary practice because such animals should be found and excluded from breeding and earlier reveal gives possible to treated.
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SALLE, B. & HEDINGER, C. (1970) Gonadal histology in children with male pseudohermaphroditism, and mixed gonadal dysgenesis. Acta endocrinologica scandinavica, 64, 211. TAUB, J. (1954) Malignant testicular tumour, cryptorchidism and polyorchidism in a pseudohermaphrodite. Journal of Urology, 71, 475. VAUGHN, J. & GONZALES-ANGULO, A. (1961) True hermaphrodite with ovarian tumour. Journal of Urol...
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